Registered Nurse (RN) Salary in South Carolina
Median annual base pay is $74,880 across 36 reported Registered Nurse (RN) salaries in South Carolina.
Updated 23 September 2025
Salary Distribution (By Percentile)
| P10 | P25 | Median | P75 | P90 |
|---|---|---|---|---|
| $68,078 | $68,078 | $74,880 | $83,200 | $86,200 |
Top Cities in South Carolina
| City | Median | Reports |
|---|---|---|
| Lancaster | $83,200 | 13 |
| Charleston | $68,078 | 19 |
Top Employers in South Carolina
| Employer | Median | Reports |
|---|---|---|
| Carnegie Health & Life Sciences Inc | $79,539 | 17 |
| Medical University Hospital Authority | $68,078 | 12 |
Registered Nurse (RN) salaries in other states
- Arizona
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- Connecticut
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- Idaho
- Illinois
- Indiana
- Iowa
- Kansas
- Kentucky
- Louisiana
- Maine
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- New Jersey
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- New York
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- North Dakota
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- Oregon
- Pennsylvania
- South Dakota
- Tennessee
- Texas
- Vermont
- Virginia
- Washington
Common questions
How much does a Registered Nurse (RN) make in South Carolina?
The median Registered Nurse (RN) salary in South Carolina is $74,880 per year, based on 36 reported salaries.
Which city in South Carolina pays Registered Nurse (RN)s the most?
Lancaster has the highest median at $83,200 per year, of the cities with enough reports to publish a median.
Which employers pay Registered Nurse (RN)s the most in South Carolina?
Of the employers with enough reports to publish a median, Carnegie Health & Life Sciences Inc is highest at $79,539 per year.
Am I underpaid as a Registered Nurse (RN)?
All Registered Nurse (RN) salaries ยท Browse salaries by role